A Biomathematical Model forPhoma TracheiphilaCitrus Resistance Screening

A Biomathematical Model of Hematotoxicity

Dynamic Circadian Modulation in a Biomathematical Model

1987 Mathematical Model of Fatigue and Performance—McCauley et al INTRODUCTION Building on the seminal two-process model of sleep regulation,1,2 biomathematical models for the prediction of fatigue, behavioral alertness and performance during periods of sleep deprivation and/or circadian misalignment instantiate a homeostatic process seeking to balance time asleep with time awake, and a circadi...

Biomathematical screening of amyloid radiotracers with clinical usefulness index

Introduction To facilitate radiotracers' development, a screening methodology using a biomathematical model and clinical usefulness index (CUI) was proposed to evaluate radiotracers' diagnostic capabilities. Methods A total of 31 amyloid positron emission tomography radiotracers were evaluated. A previously developed biomathematical model was used to simulate 1000 standardized uptake value ra...

Astronaut Scheduling Assistant: a Biomathematical Model of the Neurobehavioral Performance Capability of Space Shuttle Crews

There is considerable evidence that sleep is chronically reduced in space flight operations, in spite of recommendations that astronauts sleep 6 to 8 hrs per night while in orbit. Space shuttle crews have reported average sleep durations of 5-6 hrs in space compared to 7-8 hrs on the ground. This chronic sleep reduction is related to a combination of factors such as operational demands, noise l...

A Biomathematical Model of Pneumococcal Lung Infection and Antibiotic Treatment in Mice

Pneumonia is considered to be one of the leading causes of death worldwide. The outcome depends on both, proper antibiotic treatment and the effectivity of the immune response of the host. However, due to the complexity of the immunologic cascade initiated during infection, the latter cannot be predicted easily. We construct a biomathematical model of the murine immune response during infection...